BDBM50176525 7-hydroxy-3-(3',5'-dihydroxyphenyl)coumarin::CHEMBL200198

SMILES: Oc1ccc2cc(-c3cc(O)cc(O)c3)c(=O)oc2c1

InChI Key: InChIKey=RSNNHDKEOIZSOG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50176525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50176525 (7-hydroxy-3-(3',5'-dihydroxyphenyl)coumarin | CHEM...) Show SMILES Oc1ccc2cc(-c3cc(O)cc(O)c3)c(=O)oc2c1 Show InChI InChI=1S/C15H10O5/c16-10-2-1-8-5-13(15(19)20-14(8)7-10)9-3-11(17)6-12(18)4-9/h1-7,16-18H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Inhibition of thrombin-induced platelet aggregation in human				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50176525 (7-hydroxy-3-(3',5'-dihydroxyphenyl)coumarin | CHEM...) Show SMILES Oc1ccc2cc(-c3cc(O)cc(O)c3)c(=O)oc2c1 Show InChI InChI=1S/C15H10O5/c16-10-2-1-8-5-13(15(19)20-14(8)7-10)9-3-11(17)6-12(18)4-9/h1-7,16-18H	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Inhibition of tyrosinase				Bioorg Med Chem Lett 21: 3342-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.012 BindingDB Entry DOI: 10.7270/Q2QF8T68
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50176525 (7-hydroxy-3-(3',5'-dihydroxyphenyl)coumarin | CHEM...) Show SMILES Oc1ccc2cc(-c3cc(O)cc(O)c3)c(=O)oc2c1 Show InChI InChI=1S/C15H10O5/c16-10-2-1-8-5-13(15(19)20-14(8)7-10)9-3-11(17)6-12(18)4-9/h1-7,16-18H	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Noradrenaline induced vasorelaxant activity in intact rat aortic rings				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
					More data for this Ligand-Target Pair