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SMILES: COc1ccc(Nc2nc(NC3CC3)c3ccccc3n2)cc1

InChI Key: InChIKey=RMRSKURFSGCSFM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176795   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))		BDBM50176795
PNG
(CHEMBL3809606)
Show SMILES COc1ccc(Nc2nc(NC3CC3)c3ccccc3n2)cc1
Show InChI InChI=1S/C18H18N4O/c1-23-14-10-8-13(9-11-14)20-18-21-16-5-3-2-4-15(16)17(22-18)19-12-6-7-12/h2-5,8-12H,6-7H2,1H3,(H2,19,20,21,22)
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PubMed
n/an/a 3.56E+3n/an/an/an/an/an/a



Beijing Institute of Pharmacology& Toxicology

Curated by ChEMBL


Assay Description
Inhibition of MERTK (unknown origin) using EFPIYDFLPAKKK-CONH2 as substrate and ATP after 180 mins by microfluidic capillary electrophoresis method

Bioorg Med Chem 24: 3083-3092 (2016)


BindingDB Entry DOI: 10.7270/Q23B621J
More data for this
Ligand-Target Pair