BDBM50176885 CHEMBL3814082

SMILES: COc1ccc(cc1)C(=O)\C=C\c1cccc(F)c1O

InChI Key: InChIKey=MYWXVUPGTQHBJW-JXMROGBWSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50176885 (CHEMBL3814082) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1cccc(F)c1O Show InChI InChI=1S/C16H13FO3/c1-20-13-8-5-11(6-9-13)15(18)10-7-12-3-2-4-14(17)16(12)19/h2-10,19H,1H3/b10-7+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Binding affinity to PEST and transmembrane regions lacking N-terminal His6/MBP-tagged human MCl1 (172 to 327 residues) expressed in Escherichia coli ...				J Med Chem 59: 4152-70 (2016) BindingDB Entry DOI: 10.7270/Q2TX3H9R
					More data for this Ligand-Target Pair