BDBM50176895 6-iodo-4'-hydroxyflavone::CHEMBL388844

SMILES: Oc1ccc(cc1)-c1cc(=O)c2cc(I)ccc2o1

InChI Key: InChIKey=IFAJNNUYROKKPW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176895   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50176895 (6-iodo-4'-hydroxyflavone | CHEMBL388844) Show SMILES Oc1ccc(cc1)-c1cc(=O)c2cc(I)ccc2o1 Show InChI InChI=1S/C15H9IO3/c16-10-3-6-14-12(7-10)13(18)8-15(19-14)9-1-4-11(17)5-2-9/h1-8,17H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nagasaki University Curated by ChEMBL					Assay Description Displacement of [125I]6-iodo-4'-dimethyaminofl avone from beta amyloid (1-40) protein aggregates				J Med Chem 48: 7253-60 (2005) Article DOI: 10.1021/jm050635e BindingDB Entry DOI: 10.7270/Q2H70FC0
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50176895 (6-iodo-4'-hydroxyflavone | CHEMBL388844) Show SMILES Oc1ccc(cc1)-c1cc(=O)c2cc(I)ccc2o1 Show InChI InChI=1S/C15H9IO3/c16-10-3-6-14-12(7-10)13(18)8-15(19-14)9-1-4-11(17)5-2-9/h1-8,17H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	77.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nagasaki University Curated by ChEMBL					Assay Description Displacement of [125I]6-iodo-4'-dimethyaminofl avone from beta amyloid (1-42) protein aggregates				J Med Chem 48: 7253-60 (2005) Article DOI: 10.1021/jm050635e BindingDB Entry DOI: 10.7270/Q2H70FC0
					More data for this Ligand-Target Pair