BDBM50176899 CHEMBL3814893

SMILES: COc1ccc(C(=O)\C=C\c2cc(Cl)c(O)c(OC)c2)c(OC)c1OC

InChI Key: InChIKey=DFERJTHJGHNKRO-FNORWQNLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176899   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50176899 (CHEMBL3814893) Show SMILES COc1ccc(C(=O)\C=C\c2cc(Cl)c(O)c(OC)c2)c(OC)c1OC Show InChI InChI=1S/C19H19ClO6/c1-23-15-8-6-12(18(25-3)19(15)26-4)14(21)7-5-11-9-13(20)17(22)16(10-11)24-2/h5-10,22H,1-4H3/b7-5+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Binding affinity to PEST and transmembrane regions lacking N-terminal His6/MBP-tagged human MCl1 (172 to 327 residues) expressed in Escherichia coli ...				J Med Chem 59: 4152-70 (2016) BindingDB Entry DOI: 10.7270/Q2TX3H9R
					More data for this Ligand-Target Pair