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BDBM50176994 CHEMBL3813784

SMILES: O=C(COc1ccccc1)N[C@@H](Cc1ccccc1)C(=O)O[C@H]1CCOC1

InChI Key: InChIKey=PAMMCLXVBWLYOZ-OALUTQOASA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176994   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Procathepsin L


(Homo sapiens (Human))		BDBM50176994
PNG
(CHEMBL3813784)
Show SMILES O=C(COc1ccccc1)N[C@@H](Cc1ccccc1)C(=O)O[C@H]1CCOC1 |r|
Show InChI InChI=1S/C21H23NO5/c23-20(15-26-17-9-5-2-6-10-17)22-19(13-16-7-3-1-4-8-16)21(24)27-18-11-12-25-14-18/h1-10,18-19H,11-15H2,(H,22,23)/t18-,19-/m0/s1
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MMDB

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Similars
PubMed
n/an/an/an/a 6.00E+3n/an/an/an/a



Swiss Federal Institute of Technology (ETH)

Curated by ChEMBL


Assay Description
Activation of human liver cathepsin L using Z-FR-AMC as substrate measured for 120 mins by fluorescence assay

J Med Chem 59: 4077-86 (2016)


BindingDB Entry DOI: 10.7270/Q2FN184P
More data for this
Ligand-Target Pair