BDBM50177204 6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-3,5-difluoro-pyridin-2-yloxy]-N-cyclopropyl-isophthalamic acid trifluoro-acetic acid::CHEMBL203668

SMILES: CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NC2CC2)c1F

InChI Key: InChIKey=LJFNYBMWXSUPBU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor III/Factor VIIa (fVIIa) (Homo sapiens (Human))	BDBM50177204 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NC2CC2)c1F Show InChI InChI=1S/C29H31F2N5O5/c1-14(2)36(15(3)4)24-22(30)27(40-19-7-5-6-16(12-19)25(32)33)35-28(23(24)31)41-21-11-8-17(13-20(21)29(38)39)26(37)34-18-9-10-18/h5-8,11-15,18H,9-10H2,1-4H3,(H3,32,33)(H,34,37)(H,38,39)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50177204 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NC2CC2)c1F Show InChI InChI=1S/C29H31F2N5O5/c1-14(2)36(15(3)4)24-22(30)27(40-19-7-5-6-16(12-19)25(32)33)35-28(23(24)31)41-21-11-8-17(13-20(21)29(38)39)26(37)34-18-9-10-18/h5-8,11-15,18H,9-10H2,1-4H3,(H3,32,33)(H,34,37)(H,38,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of FIIa				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair