BDBM50177218 2-((2,5-dichloro-4-nitrophenylamino)(methoxy)methyl)quinolin-8-ol::CHEMBL202291

SMILES: COC(Nc1cc(Cl)c(cc1Cl)[N+]([O-])=O)c1ccc2cccc(O)c2n1

InChI Key: InChIKey=HEIZKNRSIZUJSG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50177218 (2-((2,5-dichloro-4-nitrophenylamino)(methoxy)methy...) Show SMILES COC(Nc1cc(Cl)c(cc1Cl)[N+]([O-])=O)c1ccc2cccc(O)c2n1 Show InChI InChI=1S/C17H13Cl2N3O4/c1-26-17(12-6-5-9-3-2-4-15(23)16(9)20-12)21-13-7-11(19)14(22(24)25)8-10(13)18/h2-8,17,21,23H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Antiviral activity against HIV1 integrase				Bioorg Med Chem Lett 16: 1005-9 (2006) Article DOI: 10.1016/j.bmcl.2005.10.083 BindingDB Entry DOI: 10.7270/Q2QR4WQD
					More data for this Ligand-Target Pair