BDBM50177275 CHEMBL204968::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methylquinolin-6-yl)-3-(4-(trifluoromethoxy)phenyl)propanamide

SMILES: CN(C)CCN(C)c1cc(C)c2cc(NC(=O)CCc3ccc(OC(F)(F)F)cc3)ccc2n1

InChI Key: InChIKey=ZRGODGYQZOLGQP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177275   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50177275 (CHEMBL204968 | N-(2-((2-(dimethylamino)ethyl)(meth...) Show SMILES CN(C)CCN(C)c1cc(C)c2cc(NC(=O)CCc3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C25H29F3N4O2/c1-17-15-23(32(4)14-13-31(2)3)30-22-11-8-19(16-21(17)22)29-24(33)12-7-18-5-9-20(10-6-18)34-25(26,27)28/h5-6,8-11,15-16H,7,12-14H2,1-4H3,(H,29,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human MCH1 receptor by SPA assay				Bioorg Med Chem Lett 16: 1070-5 (2006) Article DOI: 10.1016/j.bmcl.2005.10.066 BindingDB Entry DOI: 10.7270/Q2G73D82
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50177275 (CHEMBL204968 | N-(2-((2-(dimethylamino)ethyl)(meth...) Show SMILES CN(C)CCN(C)c1cc(C)c2cc(NC(=O)CCc3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C25H29F3N4O2/c1-17-15-23(32(4)14-13-31(2)3)30-22-11-8-19(16-21(17)22)29-24(33)12-7-18-5-9-20(10-6-18)34-25(26,27)28/h5-6,8-11,15-16H,7,12-14H2,1-4H3,(H,29,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	724	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of [3H]myo-inositol from human MCH1 receptor expressed in CHO cell by IP3 assay				Bioorg Med Chem Lett 16: 1070-5 (2006) Article DOI: 10.1016/j.bmcl.2005.10.066 BindingDB Entry DOI: 10.7270/Q2G73D82
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50177275 (CHEMBL204968 | N-(2-((2-(dimethylamino)ethyl)(meth...) Show SMILES CN(C)CCN(C)c1cc(C)c2cc(NC(=O)CCc3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C25H29F3N4O2/c1-17-15-23(32(4)14-13-31(2)3)30-22-11-8-19(16-21(17)22)29-24(33)12-7-18-5-9-20(10-6-18)34-25(26,27)28/h5-6,8-11,15-16H,7,12-14H2,1-4H3,(H,29,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in CHO cell by WC assay				Bioorg Med Chem Lett 16: 1070-5 (2006) Article DOI: 10.1016/j.bmcl.2005.10.066 BindingDB Entry DOI: 10.7270/Q2G73D82
					More data for this Ligand-Target Pair