BDBM50177304 2-biphenyl-4-yl-N-{2-[(2-dimethylamino-ethyl)-methyl-amino]-4-methyl-quinolin-6-yl}-acetamide::CHEMBL203929

SMILES: CN(C)CCN(C)c1cc(C)c2cc(NC(=O)Cc3ccc(cc3)-c3ccccc3)ccc2n1

InChI Key: InChIKey=UQHRKZZEJAOTMU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50177304 (2-biphenyl-4-yl-N-{2-[(2-dimethylamino-ethyl)-meth...) Show SMILES CN(C)CCN(C)c1cc(C)c2cc(NC(=O)Cc3ccc(cc3)-c3ccccc3)ccc2n1 Show InChI InChI=1S/C29H32N4O/c1-21-18-28(33(4)17-16-32(2)3)31-27-15-14-25(20-26(21)27)30-29(34)19-22-10-12-24(13-11-22)23-8-6-5-7-9-23/h5-15,18,20H,16-17,19H2,1-4H3,(H,30,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human MCH1 receptor by SPA assay				Bioorg Med Chem Lett 16: 1070-5 (2006) Article DOI: 10.1016/j.bmcl.2005.10.066 BindingDB Entry DOI: 10.7270/Q2G73D82
					More data for this Ligand-Target Pair