BDBM50177319 (2,4-dichlorophenyl)(4-(4-methoxyphenyl)cyclopenta[d][1,2]oxazin-7-yl)methanone::CHEMBL201909

SMILES: COc1ccc(cc1)-c1nocc2c(ccc12)C(=O)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=NHWPSAQOZSKXQI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177319   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50177319 ((2,4-dichlorophenyl)(4-(4-methoxyphenyl)cyclopenta...) Show SMILES COc1ccc(cc1)-c1nocc2c(ccc12)C(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H13Cl2NO3/c1-26-14-5-2-12(3-6-14)20-15-8-9-16(18(15)11-27-24-20)21(25)17-7-4-13(22)10-19(17)23/h2-11H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human PTP1B				Bioorg Med Chem Lett 16: 499-502 (2005) Article DOI: 10.1016/j.bmcl.2005.10.062 BindingDB Entry DOI: 10.7270/Q2319VFG
					More data for this Ligand-Target Pair