BDBM50177423 CHEMBL540105::N-(4-carbamimidoylbenzyl)-2-(3-(4-chlorophenylsulfonamido)-2-hydroxy-6-methylphenyl)acetamide hydrochloride

SMILES: Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(O)c1CC(=O)NCc1ccc(cc1)C(N)=N

InChI Key: InChIKey=VACRFYDEAFTWGB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50177423 (CHEMBL540105 | N-(4-carbamimidoylbenzyl)-2-(3-(4-c...) Show SMILES Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(O)c1CC(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C23H23ClN4O4S/c1-14-2-11-20(28-33(31,32)18-9-7-17(24)8-10-18)22(30)19(14)12-21(29)27-13-15-3-5-16(6-4-15)23(25)26/h2-11,28,30H,12-13H2,1H3,(H3,25,26)(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Inhibitory activity against thrombin				Bioorg Med Chem Lett 16: 1032-6 (2006) Article DOI: 10.1016/j.bmcl.2005.10.082 BindingDB Entry DOI: 10.7270/Q2V125K5
					More data for this Ligand-Target Pair