BDBM50177599 CHEMBL202447::[2-chloro-4-(3-methyl-pyrazol-1-yl)-phenyl]-(5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6-yl)-methanone

SMILES: Cc1ccn(n1)-c1ccc(C(=O)N2Cc3cccnc3Nc3ccccc23)c(Cl)c1

InChI Key: InChIKey=FFHVLUWEDZQYCP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177599   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50177599 (CHEMBL202447 | [2-chloro-4-(3-methyl-pyrazol-1-yl)...) Show SMILES Cc1ccn(n1)-c1ccc(C(=O)N2Cc3cccnc3Nc3ccccc23)c(Cl)c1 Show InChI InChI=1S/C23H18ClN5O/c1-15-10-12-29(27-15)17-8-9-18(19(24)13-17)23(30)28-14-16-5-4-11-25-22(16)26-20-6-2-3-7-21(20)28/h2-13H,14H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	91.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]AVP from human V2 receptor transfected in LV2 cells				Bioorg Med Chem Lett 16: 954-9 (2006) Article DOI: 10.1016/j.bmcl.2005.10.107 BindingDB Entry DOI: 10.7270/Q27945GR
					More data for this Ligand-Target Pair