BDBM50177710 (3-acetylamino-5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepten-7-yl)-acetic acid::CHEMBL201975

SMILES: CC(=O)Nc1ccc2CSc3ccc(CC(O)=O)cc3C(=O)c2c1

InChI Key: InChIKey=OWUJPQVKEBVLJL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Helicase IV (Escherichia coli (strain K12))	BDBM50177710 ((3-acetylamino-5-oxo-5,11-dihydro-10-thia-dibenzo[...) Show SMILES CC(=O)Nc1ccc2CSc3ccc(CC(O)=O)cc3C(=O)c2c1 Show InChI InChI=1S/C18H15NO4S/c1-10(20)19-13-4-3-12-9-24-16-5-2-11(7-17(21)22)6-15(16)18(23)14(12)8-13/h2-6,8H,7,9H2,1H3,(H,19,20)(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)				Bioorg Med Chem Lett 16: 923-7 (2006) Article DOI: 10.1016/j.bmcl.2005.10.110 BindingDB Entry DOI: 10.7270/Q2MS3SB8
					More data for this Ligand-Target Pair