BDBM50178619 CHEMBL3814419

SMILES: Fc1cc(cc(c1)[C@](Cc1ccccc1)(NCC(=O)CC(F)(F)F)c1ccc(Cl)cn1)C(F)(F)F

InChI Key: InChIKey=RBBUDHKIYUMXDH-QFIPXVFZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178619   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178619 (CHEMBL3814419) Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NCC(=O)CC(F)(F)F)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C24H18ClF7N2O/c25-18-6-7-21(33-13-18)22(11-15-4-2-1-3-5-15,34-14-20(35)12-23(27,28)29)16-8-17(24(30,31)32)10-19(26)9-16/h1-10,13,34H,11-12,14H2/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of CETP in human whole plasma assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to LDL/VLDL				Bioorg Med Chem Lett 26: 3278-3281 (2016) BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178619 (CHEMBL3814419) Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NCC(=O)CC(F)(F)F)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C24H18ClF7N2O/c25-18-6-7-21(33-13-18)22(11-15-4-2-1-3-5-15,34-14-20(35)12-23(27,28)29)16-8-17(24(30,31)32)10-19(26)9-16/h1-10,13,34H,11-12,14H2/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	641	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...				Bioorg Med Chem Lett 26: 3278-3281 (2016) BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair