BDBM50178994 2-(4-(4,6-bis(4-fluorophenylamino)-1,3,5-triazin-2-yl)piperazin-1-yl)ethanol::CHEMBL204910

SMILES: OCCN1CCN(CC1)c1nc(Nc2ccc(F)cc2)nc(Nc2ccc(F)cc2)n1

InChI Key: InChIKey=SPOMVEGBVZIORU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50178994 (2-(4-(4,6-bis(4-fluorophenylamino)-1,3,5-triazin-2...) Show SMILES OCCN1CCN(CC1)c1nc(Nc2ccc(F)cc2)nc(Nc2ccc(F)cc2)n1 Show InChI InChI=1S/C21H23F2N7O/c22-15-1-5-17(6-2-15)24-19-26-20(25-18-7-3-16(23)4-8-18)28-21(27-19)30-11-9-29(10-12-30)13-14-31/h1-8,31H,9-14H2,(H2,24,25,26,27,28)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair