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BDBM50179114 (2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)-3-methylhexa-2,4-dienoic acid::CHEMBL379057

SMILES: CCCN(C\C=C\C(\C)=C\C(O)=O)c1cc(cc(c1)C(C)(C)C)C(C)(C)C

InChI Key: InChIKey=NJUNLFLTZKMXMQ-NJESZQPCSA-N

Data: 3 KI 3 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50179114
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50179114 ((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity to RXRalpha				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
Ligand Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50179114 ((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity to RXRbeta				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
Ligand Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50179114 ((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity to RXRgamma				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
Ligand Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50179114 ((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	69	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Transactivation of RXRbeta in CV1 cells by cotransfection assay				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
Ligand Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50179114 ((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Transactivation of RXRalpha in CV1 cells by cotransfection assay				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
Ligand Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50179114 ((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Transactivation of RXRgamma in CV1 cells by cotransfection assay				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
Ligand Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair