BDBM50179216 3-carbomethoxy-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine::CHEMBL332375

SMILES: COC(=O)c1cccc(Nc2[nH]nc-3c2Cc2cc(OC)c(OC)cc-32)c1

InChI Key: InChIKey=SMLHMBXAZLBCAX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179216 (3-carbomethoxy-N-(6,7-dimethoxy-2,4-dihydroindeno[...) Show SMILES COC(=O)c1cccc(Nc2[nH]nc-3c2Cc2cc(OC)c(OC)cc-32)c1 Show InChI InChI=1S/C20H19N3O4/c1-25-16-9-12-8-15-18(14(12)10-17(16)26-2)22-23-19(15)21-13-6-4-5-11(7-13)20(24)27-3/h4-7,9-10H,8H2,1-3H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antiproliferative activity against PDGF-BB stimulated HCASMC				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179216 (3-carbomethoxy-N-(6,7-dimethoxy-2,4-dihydroindeno[...) Show SMILES COC(=O)c1cccc(Nc2[nH]nc-3c2Cc2cc(OC)c(OC)cc-32)c1 Show InChI InChI=1S/C20H19N3O4/c1-25-16-9-12-8-15-18(14(12)10-17(16)26-2)22-23-19(15)21-13-6-4-5-11(7-13)20(24)27-3/h4-7,9-10H,8H2,1-3H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antiproliferative activity against PDGF-BB stimulated HCASMC				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair