BDBM50179237 2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)propoxy]-1H-indol-1-yl}ethanoic acid::CHEMBL121206

SMILES: CCCc1c(OCCCOc2cccc3n(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F

InChI Key: InChIKey=GVSXYCPBNPXKCS-UHFFFAOYSA-N

Data: 1 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50179237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50179237 (2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazo...) Show SMILES CCCc1c(OCCCOc2cccc3n(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F Show InChI InChI=1S/C24H23F3N2O5/c1-2-5-16-20(9-8-17-22(16)34-28-23(17)24(25,26)27)33-13-4-12-32-19-7-3-6-18-15(19)10-11-29(18)14-21(30)31/h3,6-11H,2,4-5,12-14H2,1H3,(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	610	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Functional activity at human PPAR delta in Huh7 cells by transactivation assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50179237 (2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazo...) Show SMILES CCCc1c(OCCCOc2cccc3n(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F Show InChI InChI=1S/C24H23F3N2O5/c1-2-5-16-20(9-8-17-22(16)34-28-23(17)24(25,26)27)33-13-4-12-32-19-7-3-6-18-15(19)10-11-29(18)14-21(30)31/h3,6-11H,2,4-5,12-14H2,1H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.39E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Functional activity at human PPAR gamma in Huh7 cells by transactivation assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50179237 (2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazo...) Show SMILES CCCc1c(OCCCOc2cccc3n(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F Show InChI InChI=1S/C24H23F3N2O5/c1-2-5-16-20(9-8-17-22(16)34-28-23(17)24(25,26)27)33-13-4-12-32-19-7-3-6-18-15(19)10-11-29(18)14-21(30)31/h3,6-11H,2,4-5,12-14H2,1H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50179237 (2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazo...) Show SMILES CCCc1c(OCCCOc2cccc3n(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F Show InChI InChI=1S/C24H23F3N2O5/c1-2-5-16-20(9-8-17-22(16)34-28-23(17)24(25,26)27)33-13-4-12-32-19-7-3-6-18-15(19)10-11-29(18)14-21(30)31/h3,6-11H,2,4-5,12-14H2,1H3,(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	186	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Functional activity at human PPAR alpha in Huh7 cells by transactivation assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair