BDBM50179241 2-{4-[2-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)ethoxy]-1H-indol-1-yl}ethanoic acid::CHEMBL321815

SMILES: CCCc1c(OCCOc2cccc3n(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F

InChI Key: InChIKey=FVIOTIMMQMLVMV-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50179241 (2-{4-[2-(7-propyl-3-trifluoromethylbenzo[d]isoxazo...) Show SMILES CCCc1c(OCCOc2cccc3n(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F Show InChI InChI=1S/C23H21F3N2O5/c1-2-4-15-19(8-7-16-21(15)33-27-22(16)23(24,25)26)32-12-11-31-18-6-3-5-17-14(18)9-10-28(17)13-20(29)30/h3,5-10H,2,4,11-13H2,1H3,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Functional activity at human PPAR gamma in Huh7 cells by transactivation assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50179241 (2-{4-[2-(7-propyl-3-trifluoromethylbenzo[d]isoxazo...) Show SMILES CCCc1c(OCCOc2cccc3n(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F Show InChI InChI=1S/C23H21F3N2O5/c1-2-4-15-19(8-7-16-21(15)33-27-22(16)23(24,25)26)32-12-11-31-18-6-3-5-17-14(18)9-10-28(17)13-20(29)30/h3,5-10H,2,4,11-13H2,1H3,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair