null

SMILES: CCCc1c(OCCCOc2ccc3n(CC(O)=O)ccc3c2)ccc2c(c[nH]c12)C(=O)C(F)(F)F

InChI Key: InChIKey=GHGWDIVXERLYFN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50179245   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50179245 (2-(5-{3-[3-(2,2,2-trifluoroethyl-1-one)-7-propyl-1...) Show SMILES CCCc1c(OCCCOc2ccc3n(CC(O)=O)ccc3c2)ccc2c(c[nH]c12)C(=O)C(F)(F)F Show InChI InChI=1S/C26H25F3N2O5/c1-2-4-19-22(8-6-18-20(14-30-24(18)19)25(34)26(27,28)29)36-12-3-11-35-17-5-7-21-16(13-17)9-10-31(21)15-23(32)33/h5-10,13-14,30H,2-4,11-12,15H2,1H3,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	9.17E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Functional activity at human PPAR delta in Huh7 cells by transactivation assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50179245 (2-(5-{3-[3-(2,2,2-trifluoroethyl-1-one)-7-propyl-1...) Show SMILES CCCc1c(OCCCOc2ccc3n(CC(O)=O)ccc3c2)ccc2c(c[nH]c12)C(=O)C(F)(F)F Show InChI InChI=1S/C26H25F3N2O5/c1-2-4-19-22(8-6-18-20(14-30-24(18)19)25(34)26(27,28)29)36-12-3-11-35-17-5-7-21-16(13-17)9-10-31(21)15-23(32)33/h5-10,13-14,30H,2-4,11-12,15H2,1H3,(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Functional activity at human PPAR gamma in Huh7 cells by transactivation assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50179245 (2-(5-{3-[3-(2,2,2-trifluoroethyl-1-one)-7-propyl-1...) Show SMILES CCCc1c(OCCCOc2ccc3n(CC(O)=O)ccc3c2)ccc2c(c[nH]c12)C(=O)C(F)(F)F Show InChI InChI=1S/C26H25F3N2O5/c1-2-4-19-22(8-6-18-20(14-30-24(18)19)25(34)26(27,28)29)36-12-3-11-35-17-5-7-21-16(13-17)9-10-31(21)15-23(32)33/h5-10,13-14,30H,2-4,11-12,15H2,1H3,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Functional activity at human PPAR alpha in Huh7 cells by transactivation assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50179245 (2-(5-{3-[3-(2,2,2-trifluoroethyl-1-one)-7-propyl-1...) Show SMILES CCCc1c(OCCCOc2ccc3n(CC(O)=O)ccc3c2)ccc2c(c[nH]c12)C(=O)C(F)(F)F Show InChI InChI=1S/C26H25F3N2O5/c1-2-4-19-22(8-6-18-20(14-30-24(18)19)25(34)26(27,28)29)36-12-3-11-35-17-5-7-21-16(13-17)9-10-31(21)15-23(32)33/h5-10,13-14,30H,2-4,11-12,15H2,1H3,(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair