BDBM50179249 2-ethyl-2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)propoxy]-1H-indol-1-yl}ethanoic acid::CHEMBL411423

SMILES: CCCc1c(OCCCOc2cccc3n(ccc23)C(CC)C(O)=O)ccc2c(noc12)C(F)(F)F

InChI Key: InChIKey=DBNPMVWLTQZOKJ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179249   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50179249 (2-ethyl-2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d...) Show SMILES CCCc1c(OCCCOc2cccc3n(ccc23)C(CC)C(O)=O)ccc2c(noc12)C(F)(F)F Show InChI InChI=1S/C26H27F3N2O5/c1-3-7-17-22(11-10-18-23(17)36-30-24(18)26(27,28)29)35-15-6-14-34-21-9-5-8-20-16(21)12-13-31(20)19(4-2)25(32)33/h5,8-13,19H,3-4,6-7,14-15H2,1-2H3,(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50179249 (2-ethyl-2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d...) Show SMILES CCCc1c(OCCCOc2cccc3n(ccc23)C(CC)C(O)=O)ccc2c(noc12)C(F)(F)F Show InChI InChI=1S/C26H27F3N2O5/c1-3-7-17-22(11-10-18-23(17)36-30-24(18)26(27,28)29)35-15-6-14-34-21-9-5-8-20-16(21)12-13-31(20)19(4-2)25(32)33/h5,8-13,19H,3-4,6-7,14-15H2,1-2H3,(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Functional activity at human PPAR gamma in Huh7 cells by transactivation assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
					More data for this Ligand-Target Pair