BDBM50179351 (2-chloro-3-methyl-4H-thieno[3,2-b]pyrrol-5-yl)(4-methylpiperazin-1-yl)methanone::CHEMBL199062

SMILES: CN1CCN(CC1)C(=O)c1cc2sc(Cl)c(C)c2[nH]1

InChI Key: InChIKey=FHTHHGGIWNDYIW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50179351 ((2-chloro-3-methyl-4H-thieno[3,2-b]pyrrol-5-yl)(4-...) Show SMILES CN1CCN(CC1)C(=O)c1cc2sc(Cl)c(C)c2[nH]1 Show InChI InChI=1S/C13H16ClN3OS/c1-8-11-10(19-12(8)14)7-9(15-11)13(18)17-5-3-16(2)4-6-17/h7,15H,3-6H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from recombinant human histamine H4 receptor in SK-N-MC cells				J Med Chem 48: 8289-98 (2005) Article DOI: 10.1021/jm0502081 BindingDB Entry DOI: 10.7270/Q2C24W00
					More data for this Ligand-Target Pair