null

SMILES: N#Cc1cnc(Nc2cc(ncn2)N2CCNCC2)s1

InChI Key: InChIKey=LTSAIVCADIPFKF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50179422 (2-(6-(piperazin-1-yl)pyrimidin-4-ylamino)thiazole-...) Show SMILES N#Cc1cnc(Nc2cc(ncn2)N2CCNCC2)s1 Show InChI InChI=1S/C12H13N7S/c13-6-9-7-15-12(20-9)18-10-5-11(17-8-16-10)19-3-1-14-2-4-19/h5,7-8,14H,1-4H2,(H,15,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR expressed in HEK293 cells by KDR autophosphorylation assay				Bioorg Med Chem Lett 16: 1146-50 (2006) Article DOI: 10.1016/j.bmcl.2005.11.089 BindingDB Entry DOI: 10.7270/Q279448N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50179422 (2-(6-(piperazin-1-yl)pyrimidin-4-ylamino)thiazole-...) Show SMILES N#Cc1cnc(Nc2cc(ncn2)N2CCNCC2)s1 Show InChI InChI=1S/C12H13N7S/c13-6-9-7-15-12(20-9)18-10-5-11(17-8-16-10)19-3-1-14-2-4-19/h5,7-8,14H,1-4H2,(H,15,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 16: 1146-50 (2006) Article DOI: 10.1016/j.bmcl.2005.11.089 BindingDB Entry DOI: 10.7270/Q279448N
					More data for this Ligand-Target Pair