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SMILES: COc1ccc(NCCNC(=O)C(CC(C)C)Oc2cccc(c2)-c2ccccc2)cc1

InChI Key: InChIKey=KHMYUVAMTZRUJI-UHFFFAOYSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179537   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin K


(Homo sapiens (Human))		BDBM50179537
PNG
(2-(biphenyl-3-yloxy)-4-methyl-pentanoic acid [2-(4...)
Show SMILES COc1ccc(NCCNC(=O)C(CC(C)C)Oc2cccc(c2)-c2ccccc2)cc1
Show InChI InChI=1S/C27H32N2O3/c1-20(2)18-26(27(30)29-17-16-28-23-12-14-24(31-3)15-13-23)32-25-11-7-10-22(19-25)21-8-5-4-6-9-21/h4-15,19-20,26,28H,16-18H2,1-3H3,(H,29,30)
PDB
MMDB

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Article
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n/an/a 90n/an/an/an/an/an/a



Sankyo Co., Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant human Cathepsin K

Bioorg Med Chem Lett 16: 1502-5 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.053
BindingDB Entry DOI: 10.7270/Q2T154FS
More data for this
Ligand-Target Pair