BDBM50179671 (2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-[3-(4-methyl-benzyl)-1H-indol-4-yloxy]-tetrahydro-pyran-3,4,5-triol::CHEMBL203953

SMILES: Cc1ccc(Cc2c[nH]c3cccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c23)cc1

InChI Key: InChIKey=RPTIPWSUINVZPF-MIUGBVLSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50179671 ((2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-[3-(4-methyl-be...) Show SMILES Cc1ccc(Cc2c[nH]c3cccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c23)cc1 Show InChI InChI=1S/C22H25NO6/c1-12-5-7-13(8-6-12)9-14-10-23-15-3-2-4-16(18(14)15)28-22-21(27)20(26)19(25)17(11-24)29-22/h2-8,10,17,19-27H,9,11H2,1H3/t17-,19-,20+,21-,22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity aginst SGLT2 expressed in CHO-K1 cells				Bioorg Med Chem Lett 16: 1696-701 (2006) Article DOI: 10.1016/j.bmcl.2005.12.006 BindingDB Entry DOI: 10.7270/Q22J6BDJ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50179671 ((2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-[3-(4-methyl-be...) Show SMILES Cc1ccc(Cc2c[nH]c3cccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c23)cc1 Show InChI InChI=1S/C22H25NO6/c1-12-5-7-13(8-6-12)9-14-10-23-15-3-2-4-16(18(14)15)28-22-21(27)20(26)19(25)17(11-24)29-22/h2-8,10,17,19-27H,9,11H2,1H3/t17-,19-,20+,21-,22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity aginst SGLT1 expressed in CHO-K1 cells				Bioorg Med Chem Lett 16: 1696-701 (2006) Article DOI: 10.1016/j.bmcl.2005.12.006 BindingDB Entry DOI: 10.7270/Q22J6BDJ
					More data for this Ligand-Target Pair