BDBM50180064 4-[2-[1-(diphenylmethyl)-2-methyl-5-morpholin-4-yl-1H-indol-3-yl]-ethoxy]benzoic acid::CHEMBL372950

SMILES: Cc1c(CCOc2ccc(cc2)C(O)=O)c2cc(ccc2n1C(c1ccccc1)c1ccccc1)N1CCOCC1

InChI Key: InChIKey=MXINXELDYOYJFG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50180064 (4-[2-[1-(diphenylmethyl)-2-methyl-5-morpholin-4-yl...) Show SMILES Cc1c(CCOc2ccc(cc2)C(O)=O)c2cc(ccc2n1C(c1ccccc1)c1ccccc1)N1CCOCC1 Show InChI InChI=1S/C35H34N2O4/c1-25-31(18-21-41-30-15-12-28(13-16-30)35(38)39)32-24-29(36-19-22-40-23-20-36)14-17-33(32)37(25)34(26-8-4-2-5-9-26)27-10-6-3-7-11-27/h2-17,24,34H,18-23H2,1H3,(H,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay				J Med Chem 49: 135-58 (2006) Article DOI: 10.1021/jm0507882 BindingDB Entry DOI: 10.7270/Q2MC8ZMP
					More data for this Ligand-Target Pair