BDBM50180074 4-[[[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]-oxoacetyl]amino]benzoic acid::CHEMBL201428

SMILES: Cc1c(C(=O)C(=O)Nc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=CGEZENKSRRPLKV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50180074 (4-[[[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol...) Show SMILES Cc1c(C(=O)C(=O)Nc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H23ClN2O4/c1-19-27(29(35)30(36)33-24-15-12-22(13-16-24)31(37)38)25-18-23(32)14-17-26(25)34(19)28(20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-18,28H,1H3,(H,33,36)(H,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay				J Med Chem 49: 135-58 (2006) Article DOI: 10.1021/jm0507882 BindingDB Entry DOI: 10.7270/Q2MC8ZMP
					More data for this Ligand-Target Pair