BDBM50180095 4-[2-[[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]ethyl]sulfonyl]ethyl]benzoic acid::CHEMBL199979

SMILES: Cc1c(CCS(=O)(=O)CCc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=YKEFGFHRBSXKTI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180095   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50180095 (4-[2-[[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-...) Show SMILES Cc1c(CCS(=O)(=O)CCc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H30ClNO4S/c1-23-29(19-21-40(38,39)20-18-24-12-14-27(15-13-24)33(36)37)30-22-28(34)16-17-31(30)35(23)32(25-8-4-2-5-9-25)26-10-6-3-7-11-26/h2-17,22,32H,18-21H2,1H3,(H,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay				J Med Chem 49: 135-58 (2006) Article DOI: 10.1021/jm0507882 BindingDB Entry DOI: 10.7270/Q2MC8ZMP
					More data for this Ligand-Target Pair