BDBM50180275 CHEMBL3813874

SMILES: COc1cn(CC2CC2)nc(-c2ccnn2-c2ccccc2)c1=O

InChI Key: InChIKey=BMMJCDCWVKGXCA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180275   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50180275 (CHEMBL3813874) Show SMILES COc1cn(CC2CC2)nc(-c2ccnn2-c2ccccc2)c1=O Show InChI InChI=1S/C18H18N4O2/c1-24-16-12-21(11-13-7-8-13)20-17(18(16)23)15-9-10-19-22(15)14-5-3-2-4-6-14/h2-6,9-10,12-13H,7-8,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...				Bioorg Med Chem 24: 3447-55 (2016) BindingDB Entry DOI: 10.7270/Q2H9974G
					More data for this Ligand-Target Pair