BDBM50180444 CHEMBL203132::N*1*-(3-Bromo-phenyl)-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cycloheptene-1,8-diamine

SMILES: Nc1ccc2Oc3ncnc(Nc4cccc(Br)c4)c3NCc2c1

InChI Key: InChIKey=KLALEUZAQNFFBL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180444 (CHEMBL203132 | N*1*-(3-Bromo-phenyl)-10,11-dihydro...) Show SMILES Nc1ccc2Oc3ncnc(Nc4cccc(Br)c4)c3NCc2c1 Show InChI InChI=1S/C17H14BrN5O/c18-11-2-1-3-13(7-11)23-16-15-17(22-9-21-16)24-14-5-4-12(19)6-10(14)8-20-15/h1-7,9,20H,8,19H2,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180444 (CHEMBL203132 | N*1*-(3-Bromo-phenyl)-10,11-dihydro...) Show SMILES Nc1ccc2Oc3ncnc(Nc4cccc(Br)c4)c3NCc2c1 Show InChI InChI=1S/C17H14BrN5O/c18-11-2-1-3-13(7-11)23-16-15-17(22-9-21-16)24-14-5-4-12(19)6-10(14)8-20-15/h1-7,9,20H,8,19H2,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair