BDBM50180570 4-(4-bromo-2-fluorophenylamino)-5-fluoro-N-methoxy-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide::CHEMBL201156

SMILES: CONC(=O)c1cn(C)c(=O)c(F)c1Nc1ccc(Br)cc1F

InChI Key: InChIKey=AROVPXKNYNWWMA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50180570 (4-(4-bromo-2-fluorophenylamino)-5-fluoro-N-methoxy...) Show SMILES CONC(=O)c1cn(C)c(=O)c(F)c1Nc1ccc(Br)cc1F Show InChI InChI=1S/C14H12BrF2N3O3/c1-20-6-8(13(21)19-23-2)12(11(17)14(20)22)18-10-4-3-7(15)5-9(10)16/h3-6,18H,1-2H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Inhibitory activity aginst MEK1				J Med Chem 49: 441-4 (2006) Article DOI: 10.1021/jm050834y BindingDB Entry DOI: 10.7270/Q2571BKQ
					More data for this Ligand-Target Pair