BDBM50180659 CHEMBL3818672

SMILES: CCCCCc1ccc(\C=C\C(=O)Nc2cc(Cl)ccc2C(O)=O)cc1

InChI Key: InChIKey=MDVFITMPFHDRBZ-JLHYYAGUSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Twik-RElated Potassium (K+) channel 1 (TREK1) (Homo sapiens (Human))	BDBM50180659 (CHEMBL3818672) Show SMILES CCCCCc1ccc(\C=C\C(=O)Nc2cc(Cl)ccc2C(O)=O)cc1 Show InChI InChI=1S/C21H22ClNO3/c1-2-3-4-5-15-6-8-16(9-7-15)10-13-20(24)23-19-14-17(22)11-12-18(19)21(25)26/h6-14H,2-5H2,1H3,(H,23,24)(H,25,26)/b13-10+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Universit£ Clermont Auvergne Curated by ChEMBL					Assay Description Activation of human TREK1 expressed in CHO cells assessed as increase in channel currents at +50 mV relative to control				J Med Chem 59: 5149-57 (2016) BindingDB Entry DOI: 10.7270/Q2319XSS
					More data for this Ligand-Target Pair