BDBM50180791 CHEMBL3819324

SMILES: OC(c1nccs1)(c1ccc(C#N)c(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=WTCVPHOYLWSKPM-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50180791 (CHEMBL3819324) Show SMILES OC(c1nccs1)(c1ccc(C#N)c(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C13H6F6N2OS/c14-12(15,16)9-5-8(2-1-7(9)6-20)11(22,13(17,18)19)10-21-3-4-23-10/h1-5,22H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Modulation of human androgen receptor expressed in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assay				ACS Med Chem Lett 7: 83-8 (2016) BindingDB Entry DOI: 10.7270/Q2K35WMN
					More data for this Ligand-Target Pair