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BDBM50180885 CHEMBL3818950

SMILES: [H][C@]12CC[C@@]3([H])[C@H](C)[C@@](C)(COC)CC[C@]3([H])[C@@]1(C)CC[C@H](C2)OC(=O)CCC(O)=O

InChI Key: InChIKey=IRGDTFDMPBWMMN-NLMUFCCYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180885   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)		BDBM50180885
PNG
(CHEMBL3818950)
Show SMILES [H][C@]12CC[C@@]3([H])[C@H](C)[C@@](C)(COC)CC[C@]3([H])[C@@]1(C)CC[C@H](C2)OC(=O)CCC(O)=O |r|
Show InChI InChI=1S/C23H38O5/c1-15-18-6-5-16-13-17(28-21(26)8-7-20(24)25)9-12-23(16,3)19(18)10-11-22(15,2)14-27-4/h15-19H,5-14H2,1-4H3,(H,24,25)/t15-,16+,17+,18-,19-,22+,23-/m0/s1
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PC sid
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PubMed
n/an/a 2.92E+4n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of recombinant rat GluN1a/GluN2B co-expressed in HEK293 cells assessed as suppression of glutamate-induced current by patch-clamp method

J Med Chem 59: 4724-39 (2016)


BindingDB Entry DOI: 10.7270/Q28K7C05
More data for this
Ligand-Target Pair