BDBM50181261 3-(3-(1H-imidazol-1-yl)propyl)-1-(4-bromobenzyl)-5-methyl-5-(naphthalen-1-yl)imidazolidine-2,4-dione::CHEMBL438264

SMILES: CC1(N(Cc2ccc(Br)cc2)C(=O)N(CCCn2ccnc2)C1=O)c1cccc2ccccc12

InChI Key: InChIKey=IOTNSECWYWCDGM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) Chain B (Homo sapiens (Human))	BDBM50181261 (3-(3-(1H-imidazol-1-yl)propyl)-1-(4-bromobenzyl)-5...) Show SMILES CC1(N(Cc2ccc(Br)cc2)C(=O)N(CCCn2ccnc2)C1=O)c1cccc2ccccc12 Show InChI InChI=1S/C27H25BrN4O2/c1-27(24-9-4-7-21-6-2-3-8-23(21)24)25(33)31(16-5-15-30-17-14-29-19-30)26(34)32(27)18-20-10-12-22(28)13-11-20/h2-4,6-14,17,19H,5,15-16,18H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Keimyung University Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase				Bioorg Med Chem Lett 16: 1954-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.074 BindingDB Entry DOI: 10.7270/Q2280754
					More data for this Ligand-Target Pair