null

SMILES: OC(CCC1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)Cc1cccc(Cl)c1

InChI Key: InChIKey=APXHYSJSTXRVDF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50181277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50181277 (4-(3-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...) Show SMILES OC(CCC1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C24H28ClNO4/c25-20-5-1-3-18(15-20)16-22(27)12-10-21-11-13-23(28)26(21)14-2-4-17-6-8-19(9-7-17)24(29)30/h1,3,5-9,15,21-22,27H,2,4,10-14,16H2,(H,29,30)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to human EP1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 1799-802 (2006) Article DOI: 10.1016/j.bmcl.2006.01.018 BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Rattus norvegicus)	BDBM50181277 (4-(3-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...) Show SMILES OC(CCC1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C24H28ClNO4/c25-20-5-1-3-18(15-20)16-22(27)12-10-21-11-13-23(28)26(21)14-2-4-17-6-8-19(9-7-17)24(29)30/h1,3,5-9,15,21-22,27H,2,4,10-14,16H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	425	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat EP4 transfected in HEK293 cells by cAMP accumulation				Bioorg Med Chem Lett 16: 1799-802 (2006) Article DOI: 10.1016/j.bmcl.2006.01.018 BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Rattus norvegicus)	BDBM50181277 (4-(3-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...) Show SMILES OC(CCC1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C24H28ClNO4/c25-20-5-1-3-18(15-20)16-22(27)12-10-21-11-13-23(28)26(21)14-2-4-17-6-8-19(9-7-17)24(29)30/h1,3,5-9,15,21-22,27H,2,4,10-14,16H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to rat EP4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 1799-802 (2006) Article DOI: 10.1016/j.bmcl.2006.01.018 BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Rattus norvegicus)	BDBM50181277 (4-(3-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...) Show SMILES OC(CCC1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C24H28ClNO4/c25-20-5-1-3-18(15-20)16-22(27)12-10-21-11-13-23(28)26(21)14-2-4-17-6-8-19(9-7-17)24(29)30/h1,3,5-9,15,21-22,27H,2,4,10-14,16H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to rat EP2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 1799-802 (2006) Article DOI: 10.1016/j.bmcl.2006.01.018 BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50181277 (4-(3-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...) Show SMILES OC(CCC1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C24H28ClNO4/c25-20-5-1-3-18(15-20)16-22(27)12-10-21-11-13-23(28)26(21)14-2-4-17-6-8-19(9-7-17)24(29)30/h1,3,5-9,15,21-22,27H,2,4,10-14,16H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to human EP3 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 1799-802 (2006) Article DOI: 10.1016/j.bmcl.2006.01.018 BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5
					More data for this Ligand-Target Pair