BDBM50181279 7-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxopyrrolidin-1-yl)heptanoic acid::CHEMBL204058

SMILES: OC(CCC1CCC(=O)N1CCCCCCC(O)=O)Cc1cccc(Cl)c1

InChI Key: InChIKey=NGRWIKNLASBEQP-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP2 subtype (Rattus norvegicus)	BDBM50181279 (7-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxopyrr...) Show SMILES OC(CCC1CCC(=O)N1CCCCCCC(O)=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C21H30ClNO4/c22-17-7-5-6-16(14-17)15-19(24)11-9-18-10-12-20(25)23(18)13-4-2-1-3-8-21(26)27/h5-7,14,18-19,24H,1-4,8-13,15H2,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to rat EP2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 1799-802 (2006) Article DOI: 10.1016/j.bmcl.2006.01.018 BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Rattus norvegicus)	BDBM50181279 (7-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxopyrr...) Show SMILES OC(CCC1CCC(=O)N1CCCCCCC(O)=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C21H30ClNO4/c22-17-7-5-6-16(14-17)15-19(24)11-9-18-10-12-20(25)23(18)13-4-2-1-3-8-21(26)27/h5-7,14,18-19,24H,1-4,8-13,15H2,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to rat EP4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 1799-802 (2006) Article DOI: 10.1016/j.bmcl.2006.01.018 BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Rattus norvegicus)	BDBM50181279 (7-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxopyrr...) Show SMILES OC(CCC1CCC(=O)N1CCCCCCC(O)=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C21H30ClNO4/c22-17-7-5-6-16(14-17)15-19(24)11-9-18-10-12-20(25)23(18)13-4-2-1-3-8-21(26)27/h5-7,14,18-19,24H,1-4,8-13,15H2,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8.80	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat EP4 transfected in HEK293 cells by cAMP accumulation				Bioorg Med Chem Lett 16: 1799-802 (2006) Article DOI: 10.1016/j.bmcl.2006.01.018 BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5
					More data for this Ligand-Target Pair