BDBM50181302 4-amino-5-(1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one::CHEMBL205406

SMILES: Nc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2sccc12

InChI Key: InChIKey=QFTKAOIMHAWUBL-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50181302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM50181302 (4-amino-5-(1H-benzo[d]imidazol-2-yl)thieno[2,3-b]p...) Show SMILES Nc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2sccc12 Show InChI InChI=1S/C14H10N4OS/c15-11-7-5-6-20-14(7)18-13(19)10(11)12-16-8-3-1-2-4-9(8)17-12/h1-6H,(H,16,17)(H3,15,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	691	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta				Bioorg Med Chem Lett 16: 2247-51 (2006) Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50181302 (4-amino-5-(1H-benzo[d]imidazol-2-yl)thieno[2,3-b]p...) Show SMILES Nc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2sccc12 Show InChI InChI=1S/C14H10N4OS/c15-11-7-5-6-20-14(7)18-13(19)10(11)12-16-8-3-1-2-4-9(8)17-12/h1-6H,(H,16,17)(H3,15,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	348	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibitory activity against FGFR1				Bioorg Med Chem Lett 16: 2247-51 (2006) Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Mus musculus)	BDBM50181302 (4-amino-5-(1H-benzo[d]imidazol-2-yl)thieno[2,3-b]p...) Show SMILES Nc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2sccc12 Show InChI InChI=1S/C14H10N4OS/c15-11-7-5-6-20-14(7)18-13(19)10(11)12-16-8-3-1-2-4-9(8)17-12/h1-6H,(H,16,17)(H3,15,18,19)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR2				Bioorg Med Chem Lett 16: 2247-51 (2006) Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50181302 (4-amino-5-(1H-benzo[d]imidazol-2-yl)thieno[2,3-b]p...) Show SMILES Nc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2sccc12 Show InChI InChI=1S/C14H10N4OS/c15-11-7-5-6-20-14(7)18-13(19)10(11)12-16-8-3-1-2-4-9(8)17-12/h1-6H,(H,16,17)(H3,15,18,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR1				Bioorg Med Chem Lett 16: 2247-51 (2006) Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777
					More data for this Ligand-Target Pair