BDBM50181303 4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)-1,7-naphthyridin-2(1H)-one::CHEMBL204985

SMILES: Nc1c(-c2nc3ncccc3[nH]2)c(=O)[nH]c2cnccc12

InChI Key: InChIKey=SNYMIRFSGCNEHH-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50181303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM50181303 (4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)-1,7-naph...) Show SMILES Nc1c(-c2nc3ncccc3[nH]2)c(=O)[nH]c2cnccc12 Show InChI InChI=1S/C14H10N6O/c15-11-7-3-5-16-6-9(7)19-14(21)10(11)13-18-8-2-1-4-17-12(8)20-13/h1-6H,(H3,15,19,21)(H,17,18,20)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta				Bioorg Med Chem Lett 16: 2247-51 (2006) Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50181303 (4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)-1,7-naph...) Show SMILES Nc1c(-c2nc3ncccc3[nH]2)c(=O)[nH]c2cnccc12 Show InChI InChI=1S/C14H10N6O/c15-11-7-3-5-16-6-9(7)19-14(21)10(11)13-18-8-2-1-4-17-12(8)20-13/h1-6H,(H3,15,19,21)(H,17,18,20)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR1				Bioorg Med Chem Lett 16: 2247-51 (2006) Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50181303 (4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)-1,7-naph...) Show SMILES Nc1c(-c2nc3ncccc3[nH]2)c(=O)[nH]c2cnccc12 Show InChI InChI=1S/C14H10N6O/c15-11-7-3-5-16-6-9(7)19-14(21)10(11)13-18-8-2-1-4-17-12(8)20-13/h1-6H,(H3,15,19,21)(H,17,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibitory activity against FGFR1				Bioorg Med Chem Lett 16: 2247-51 (2006) Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Mus musculus)	BDBM50181303 (4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)-1,7-naph...) Show SMILES Nc1c(-c2nc3ncccc3[nH]2)c(=O)[nH]c2cnccc12 Show InChI InChI=1S/C14H10N6O/c15-11-7-3-5-16-6-9(7)19-14(21)10(11)13-18-8-2-1-4-17-12(8)20-13/h1-6H,(H3,15,19,21)(H,17,18,20)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR2				Bioorg Med Chem Lett 16: 2247-51 (2006) Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777
					More data for this Ligand-Target Pair