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SMILES: Oc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ncccc12

InChI Key: InChIKey=QRYNTGJRIPZSPM-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50181309   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50181309
PNG
(3-(1H-benzo[d]imidazol-2-yl)-4-hydroxy-1,8-naphthy...)
Show SMILES Oc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ncccc12
Show InChI InChI=1S/C15H10N4O2/c20-12-8-4-3-7-16-13(8)19-15(21)11(12)14-17-9-5-1-2-6-10(9)18-14/h1-7H,(H,17,18)(H2,16,19,20,21)
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PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Chiron Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against FGFR1


Bioorg Med Chem Lett 16: 2247-51 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.020
BindingDB Entry DOI: 10.7270/Q2NZ8777
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1


(Homo sapiens (Human))
BDBM50181309
PNG
(3-(1H-benzo[d]imidazol-2-yl)-4-hydroxy-1,8-naphthy...)
Show SMILES Oc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ncccc12
Show InChI InChI=1S/C15H10N4O2/c20-12-8-4-3-7-16-13(8)19-15(21)11(12)14-17-9-5-1-2-6-10(9)18-14/h1-7H,(H,17,18)(H2,16,19,20,21)
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n/an/a 3.94E+3n/an/an/an/an/an/a



Chiron Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against VEGFR1


Bioorg Med Chem Lett 16: 2247-51 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.020
BindingDB Entry DOI: 10.7270/Q2NZ8777
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM50181309
PNG
(3-(1H-benzo[d]imidazol-2-yl)-4-hydroxy-1,8-naphthy...)
Show SMILES Oc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ncccc12
Show InChI InChI=1S/C15H10N4O2/c20-12-8-4-3-7-16-13(8)19-15(21)11(12)14-17-9-5-1-2-6-10(9)18-14/h1-7H,(H,17,18)(H2,16,19,20,21)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Chiron Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against VEGFR2


Bioorg Med Chem Lett 16: 2247-51 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.020
BindingDB Entry DOI: 10.7270/Q2NZ8777
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Mus musculus (mouse))
BDBM50181309
PNG
(3-(1H-benzo[d]imidazol-2-yl)-4-hydroxy-1,8-naphthy...)
Show SMILES Oc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ncccc12
Show InChI InChI=1S/C15H10N4O2/c20-12-8-4-3-7-16-13(8)19-15(21)11(12)14-17-9-5-1-2-6-10(9)18-14/h1-7H,(H,17,18)(H2,16,19,20,21)
KEGG

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PC cid
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UniChem

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Article
PubMed
n/an/a 6.53E+3n/an/an/an/an/an/a



Chiron Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against PDGFRbeta


Bioorg Med Chem Lett 16: 2247-51 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.020
BindingDB Entry DOI: 10.7270/Q2NZ8777
More data for this
Ligand-Target Pair