BDBM50181338 3-(4-tert-butylbenzyloxy)-N-(5-chlorobenzo[d]oxazol-2-yl)benzenesulfonamide::CHEMBL382691

SMILES: CC(C)(C)c1ccc(COc2cccc(c2)S(=O)(=O)Nc2nc3cc(Cl)ccc3o2)cc1

InChI Key: InChIKey=BSEOJYGCRSQABK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50181338 (3-(4-tert-butylbenzyloxy)-N-(5-chlorobenzo[d]oxazo...) Show SMILES CC(C)(C)c1ccc(COc2cccc(c2)S(=O)(=O)Nc2nc3cc(Cl)ccc3o2)cc1 Show InChI InChI=1S/C24H23ClN2O4S/c1-24(2,3)17-9-7-16(8-10-17)15-30-19-5-4-6-20(14-19)32(28,29)27-23-26-21-13-18(25)11-12-22(21)31-23/h4-14H,15H2,1-3H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human FBPase1				Bioorg Med Chem Lett 16: 1807-10 (2006) Article DOI: 10.1016/j.bmcl.2006.01.014 BindingDB Entry DOI: 10.7270/Q2J965ZK
					More data for this Ligand-Target Pair