BDBM50181353 2,5-dichloro-N-(4-(1,2-dihydropyridin-4-yl)benzo[d]oxazol-2-yl)benzenesulfonamide::CHEMBL204931

SMILES: Clc1ccc(Cl)c(c1)S(=O)(=O)Nc1nc2c(cccc2o1)C1=CC=NCC1

InChI Key: InChIKey=YSFUNDKXZMFQFA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181353   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50181353 (2,5-dichloro-N-(4-(1,2-dihydropyridin-4-yl)benzo[d...) Show SMILES Clc1ccc(Cl)c(c1)S(=O)(=O)Nc1nc2c(cccc2o1)C1=CC=NCC1 |c:26,t:24| Show InChI InChI=1S/C18H13Cl2N3O3S/c19-12-4-5-14(20)16(10-12)27(24,25)23-18-22-17-13(2-1-3-15(17)26-18)11-6-8-21-9-7-11/h1-6,8,10H,7,9H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human FBPase1				Bioorg Med Chem Lett 16: 1807-10 (2006) Article DOI: 10.1016/j.bmcl.2006.01.014 BindingDB Entry DOI: 10.7270/Q2J965ZK
					More data for this Ligand-Target Pair