BDBM50181356 CHEMBL381757::N-(5-tert-butylbenzo[d]oxazol-2-yl)-2,5-dichlorobenzenesulfonamide

SMILES: CC(C)(C)c1ccc2oc(NS(=O)(=O)c3cc(Cl)ccc3Cl)nc2c1

InChI Key: InChIKey=INXAUNIASXQDEB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50181356 (CHEMBL381757 | N-(5-tert-butylbenzo[d]oxazol-2-yl)...) Show SMILES CC(C)(C)c1ccc2oc(NS(=O)(=O)c3cc(Cl)ccc3Cl)nc2c1 Show InChI InChI=1S/C17H16Cl2N2O3S/c1-17(2,3)10-4-7-14-13(8-10)20-16(24-14)21-25(22,23)15-9-11(18)5-6-12(15)19/h4-9H,1-3H3,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human FBPase1				Bioorg Med Chem Lett 16: 1807-10 (2006) Article DOI: 10.1016/j.bmcl.2006.01.014 BindingDB Entry DOI: 10.7270/Q2J965ZK
					More data for this Ligand-Target Pair