BDBM50181405 CHEMBL381507::N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide

SMILES: Cc1onc(c1C(=O)NCCCN1CCC2(CCc3ccccc23)CC1)-c1ccccc1

InChI Key: InChIKey=SGSDMRAOGDTNHU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181405 (CHEMBL381507 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES Cc1onc(c1C(=O)NCCCN1CCC2(CCc3ccccc23)CC1)-c1ccccc1 Show InChI InChI=1S/C27H31N3O2/c1-20-24(25(29-32-20)22-9-3-2-4-10-22)26(31)28-16-7-17-30-18-14-27(15-19-30)13-12-21-8-5-6-11-23(21)27/h2-6,8-11H,7,12-19H2,1H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair