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SMILES: Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC=C)c2ccccc12

InChI Key: InChIKey=SCAFTPGICAISGW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181600   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50181600
PNG
(1-but-3-enyl-3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]t...)
Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC=C)c2ccccc12 |t:3|
Show InChI InChI=1S/C20H17N3O4S/c1-2-3-12-23-15-10-6-4-8-13(15)18(24)17(20(23)25)19-21-14-9-5-7-11-16(14)28(26,27)22-19/h2,4-11,24H,1,3,12H2,(H,21,22)
UniProtKB/TrEMBL

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PC sid
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Article
PubMed
n/an/a 90n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay

J Med Chem 49: 971-83 (2006)


Article DOI: 10.1021/jm050855s
BindingDB Entry DOI: 10.7270/Q2N29WJJ
More data for this
Ligand-Target Pair