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SMILES: Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCCC#C)c2ccccc12

InChI Key: InChIKey=YZSVHDGORPWDBT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181614   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50181614
PNG
(3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-y...)
Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCCC#C)c2ccccc12 |t:3|
Show InChI InChI=1S/C21H17N3O4S/c1-2-3-8-13-24-16-11-6-4-9-14(16)19(25)18(21(24)26)20-22-15-10-5-7-12-17(15)29(27,28)23-20/h1,4-7,9-12,25H,3,8,13H2,(H,22,23)
UniProtKB/TrEMBL

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UniChem

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Article
PubMed
n/an/a 179n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay

J Med Chem 49: 971-83 (2006)


Article DOI: 10.1021/jm050855s
BindingDB Entry DOI: 10.7270/Q2N29WJJ
More data for this
Ligand-Target Pair