BDBM50181659 4-[3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]benzothiadiazin-3-yl)-4-hydroxy-2-oxo-1Hquinolinyl]butyrronitrile::CHEMBL201567

SMILES: Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCCC#N)c2ccccc12

InChI Key: InChIKey=BWIZWJHGEIDQDD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50181659 (4-[3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]benzothiadi...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCCC#N)c2ccccc12 |t:3| Show InChI InChI=1S/C20H16N4O4S/c21-11-5-6-12-24-15-9-3-1-7-13(15)18(25)17(20(24)26)19-22-14-8-2-4-10-16(14)29(27,28)23-19/h1-4,7-10,25H,5-6,12H2,(H,22,23)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	172	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair