BDBM50181803 3,3',5,5'-tetraiodothyronamine::CHEMBL201623
SMILES: NCCc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1
InChI Key: InChIKey=NMRKJTPVKAFIII-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trace amine-associated receptor 1 (TAAR1) (Rattus norvegicus (Rat)) | BDBM50181803 (3,3',5,5'-tetraiodothyronamine | CHEMBL201623) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
University of California at San Francisco Curated by ChEMBL | Assay Description Activity at rat TAAR1 by measuring cAMP accumulation in HEK293 cells | J Med Chem 49: 1101-12 (2006) Article DOI: 10.1021/jm0505718 BindingDB Entry DOI: 10.7270/Q2416WNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (TAAR1) (Mus musculus (Mouse)) | BDBM50181803 (3,3',5,5'-tetraiodothyronamine | CHEMBL201623) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
University of California at San Francisco Curated by ChEMBL | Assay Description Activity at mouse TAAR1 by measuring cAMP accumulation in HEK293 cells | J Med Chem 49: 1101-12 (2006) Article DOI: 10.1021/jm0505718 BindingDB Entry DOI: 10.7270/Q2416WNR | |||||||||||
More data for this Ligand-Target Pair |