BDBM50181943 2-[4-(biphenyl-3-ylmethoxy)-phenyl]-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid::CHEMBL205337

SMILES: OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OCc2cccc(c2)-c2ccccc2)cc1

InChI Key: InChIKey=NDLDNPSOGSPFET-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50181943 (2-[4-(biphenyl-3-ylmethoxy)-phenyl]-1-cyclohexyl-1...) Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OCc2cccc(c2)-c2ccccc2)cc1 Show InChI InChI=1S/C33H30N2O3/c36-33(37)27-16-19-31-30(21-27)34-32(35(31)28-12-5-2-6-13-28)25-14-17-29(18-15-25)38-22-23-8-7-11-26(20-23)24-9-3-1-4-10-24/h1,3-4,7-11,14-21,28H,2,5-6,12-13,22H2,(H,36,37)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b NS5B RNA dependent RNA polymerase				Bioorg Med Chem Lett 16: 1859-63 (2006) Article DOI: 10.1016/j.bmcl.2006.01.032 BindingDB Entry DOI: 10.7270/Q2BK1BX6
					More data for this Ligand-Target Pair